Day 1: Diagnosis and Drug Treatment

Monday, March 12, 2018

9:00 amRegistration and Breakfast Bites – Visit Exhibits
9:30 amWelcome Address: Manfred Schubert-Zsilavecz, Volker Seifert, Felix Rosenow
Debate: Diagnosis
Chairs/Panel: F. Rosenow, S. Knake, H. Lüders
10:00 amEpilepsy Diagnosis standard algorithms are useful. Stephan Schuele, Chicago, USA
10:20 amEpilepsy Diagnosis needs to be individualized. Sebastian Bauer, Frankfurt, Germany
10:40 amDiscussion
Diagnostic approaches to differentiate focal from generalized epilepsy
Chairs/Panel: J. Duncan, P. Kahane, N. Lacuey
10:50 amClinical History and Semiology. Hans Lüders, Cleveland, USA
11:10 amNeuroimaging. Susanne Knake, Marburg, Germany
11:30 amEEG. Guadalupe Fernandez-Baca Vaca, Cleveland, USA
11:50 amThe role of genetic testing. Karl Martin Klein, Frankfurt, Germany
12:10 pmCase Discussion: Patient with generalized features and focal epilepsy or vice versa. Tim Wehner, Bochum, Germany
12:30 pmLunch Break – Visit Exhibits and Posters

Industry symposium sponsored by GW-Pharmaceuticals
Chair: A. Strzelczyk
  • Epileptic encephalopathies in adulthood. Karl Martin Klein, Frankfurt, Germany
  • Evolution of diagnostic criteria of LGS with age. Alexis Arzimanoglou, Lyon, France
Drug Treatment
Chairs/Panel: H. Cross, R. Guerrini, S. Schubert-Bast
1:30 pmKeynote lecture 1: Personalized epilepsy treatment – Concept and state of the art. Matthew Walker, London, UK
Debate: Modern AED treatment of focal epilepsy
2:15 pmOne strategy fits all – AED treatment can be standardized. Günter Krämer, Zurich, Switzerland
2:35 pmConsider all patient characteristics – AED treatment should be individualized! Felix Rosenow, Frankfurt, Germany
2:55 pmDiscussion
3:05 pmPrecision Medicine approaches based on genetics. Karl Martin Klein, Frankfurt, Germany
3:25 pmCase Discussion: Individualized treatment. Philipp Reif, Frankfurt, Germany
3:45 pmCoffee Break – Visit Exhibits and Posters
Individualized treatment approaches
Chairs/Panel: E. Hirsch, M. Sperling, R. Kälviäinen
4:15 pmNodular Heterotopia: Does MRI and genetic classification allow indivualized treatment? Renzo Guerrini, Florence, Italy
4:35 pmTSC: Disease modifying treatment with mTOR pathway inhibitors. Preventive vs. first line vs. add on therapy? Susanne Schubert-Bast, Frankfurt, Germany
4:55 pmGLUT1-deficiency: Ketogenic diet. Yvonne Weber, Tübingen, Germany
5:15 pmDravet-Syndrome: a) Cannabinoids. Helen Cross, London, UK
5:35 pmDravet-Syndrome: b) Fenfluramine. Tilman Polster, Bielefeld, Germany
5:55 pmDravet-Syndrome: c) Burden of disease. Adam Strzelczyk, Frankfurt, Germany
6:15 pmCase Discussion: Mesial temporal lobe epilepsy. Soheyl Noachtar, Munich, Germany
6:35 pmDiscussion
6:45 pmKeynote lecture 2: How to treat patients with a high SUDEP risk. Samden Lhatoo, Cleveland, USA
7:30 pmAdjourn for the Day

Day 2: Presurgical Diagnosis and Epilepsy Surgery

Tuesday, March 13, 2018

8:00 amRegistration and Breakfast Bites – Visit Exhibits
Keynote Lectures
Chairs/Panel: A. Arzimanoglou, T. Polster, B. Diehl
8:30 amKeynote lecture 3: Seizure detection and prediction to individualize treatment. Mark Cook, Melbourne, Australia
9:15 amKeynote lecture 4: Special considerations in the pediatric population. Helen Cross, London, UK
Presurgical diagnosis of epilepsy. Noninvasive methods 1
Chairs/Panel: S. Schuele, S. Rampp, W. van Paesschen
10:00 amMRI in FCD: How to increase sensitivity? Niels Focke, Göttingen, Germany
10:20 amEEG-biomarkers of the epileptogenic zone. Hajo M. Hamer, Erlangen, Germany
10:40 amCoffee Break – Visit Exhibits and Posters
Presurgical diagnosis of epilepsy. Noninvasive methods 2
Chairs/Panel: S. Noachtar, E. Trinka, H. Lüders
11:10 amMEG: The contribution of magnetic (and EEG) source imaging and connectomics. Stefan Rampp, Erlangen, Germany
11:30 amIctal SPECT. Wim van Paesschen, Leuven, Belgium
11:50 amThe role of PET today. Francine Chassoux, Paris, France
12:10 pmNeuropsychology: Diagnostic and predictive? Anke Hermsen, Frankfurt, Germany
12:30 pmCase Discussion: When are invasive studies necessary? Philippe Kahane, Grenoble, France
12:50 pmLunch Break – Visit Exhibits and Posters
Tour through Poster Presentations
Presurgical diagnosis of epilepsy. Invasive methods
Chairs/Panel: P. Kahane, N. Tandon, T. Freiman
1:50 pmIndication: sEEG, subdural electrodes or both – do we need standards? Soheyl Noachtar, Munich, Germany
2:10 pmsEEG in TSC. Edouard Hirsch, Strasbourg, France
2:30 pmInvasive electrodes to access cognitive function. Beate Diehl, London, UK
2:50 pmCurrent value of intraoperative ECoG. Karl Rössler, Erlangen, Germany
3:10 pmCase Discussion: Patient with both SEEG and subdural electrodes? Nuria Lacuey Lecumberri, Cleveland, USA
Epilepsy Surgery Debate: Scope and limitations of epilepsy surgery
Chairs/Panel: H. Hamer, S. Chabardes, A. McEvoy
3:30 pmEpilepsy surgery is underused! Michael Sperling, Philadelphia, USA
3:50 pmEpilepsy surgery is overused! John Duncan, London, UK
4:10 pmDiscussion
4:20 pmCase Discussion: Is there a place for surgical treatment of non-pharmacoresistent epilepsy? Bernhard Steinhoff, Kork, Germany
4:40 pmCoffee Break – Visit Exhibits and Posters
Indication, cost and safety of epilepsy surgery
Chairs/Panel: B. Steinhoff, M. Sperling, S. Lhatoo
5:10 pmMorbidity and mortality in the epilepsy monitoring unit: Can we do better? Eugen Trinka, Salzburg, Austria
5:30 pmIs epilepsy surgery cost effective? Adam Strzelczyk, Frankfurt, Germany
6:10 pmDiscussion
6:20 pmAdjourn for the Day
7:30 pmReception

Day 3: Epilepsy Surgery and Beyond

Wednesday, March 14, 2018

8:00 amRegistration and Breakfast Bites – Visit Exhibits
Surgical approaches
Chairs/Panel: K. Rössler, H. Hamer, T. Freiman
8:30 amResective vs. disconnection surgery? Stephan Chabardes, Grenoble, France
8:50 amResection of hand motor area: when can we expect preservation of meaningful grasp? Jonathan Miller, Cleveland, USA
9:10 amTechniques to preserve visual function. Andrew McEvoy, London, UK
Debate: Which surgical approach for mTLE?
Chairs/Panel: J. Miller, S. Chabardes, N. Tandon
9:30 amThe subtemporal approach is the best for most patients. Thomas Freiman, Frankfurt, Germany
9:50 amThe surgical approach should be individualized. Andrew McEvoy, London, UK
10:10 amCoffee Break – Visit Exhibits and Posters
Novel treatment approaches, specific etiologies
Chairs: B. Diehl, A. McEvoy
10:40 amStereotactic laser thermal ablation for mTLE-HS and nodular heterotopia. Nitin Tandon, Houston, USA
11:00 amEpilepsy surgery after limbic encephalitis. Christian Bien, Bielefeld, Germany
11:20 amRadio frequency ablation for FCD. Jörg Wellmer, Bochum, Germany
11:40 amEpilepsy surgery for temporal Encephaloceles. Reetta Kälviäinen, Kuopio, Finland
12:00 pmFocused ultra sound – useful to remove epileptogenic lesions? Hartmut Vatter, Bonn, Germany
12:20 pmIntraventricular drug application. Mark Cook, Melbourne, Australia
12:40 pmTissue modification (transfection, DREDDS, Optokinetics). Matthew Walker, London, UK
1:00 pmAward ceremony for the best poster presentation
1:15 pmLunch Break – Visit Exhibits and Posters
Stimulation techniques, postsurgical outcome prediction and management
Chairs/Panel: R. Kälviäinen, S. Lhatoo, K. M. Klein
2:00 pmKeynote lecture 5: Current and future role of stimulation techniques VNS-SANTE-RNS. Andreas Schulze-Bonhage, Freiburg, Germany
2:45 pmPostoperative cognitive sequelae. Christoph Helmstaedter, Bonn, Germany
3:05 pmEpigenetics in the neuropathological diagnosis of epilepsy. Patrick Harter, Frankfurt, Germany
3:25 pmPostoperative predictors of individual seizure outcome: EEG, Imaging. Susanne Knake, Marburg, Germany
3:45 pmNeuropathology of FCD today and in the future, predictive of outcome. Albert Becker, Bonn, Germany
4:05 pmFurther management when surgery has failed. Alexis Arzimanoglou, Lyon, France
4:25 pmCoffee Break
4:55 pmCase Discussion – Bring your own Cases
6:00 pmColloquium Adjourns